Publications

Selected Publications Related to NanoCav Technologies

Advanced Cell Engineering Platforms

  1. Wu, T.H., Sagullo, E., Case, D., Zheng, X., Li, Y., Hong, J.S., TeSlaa, T., Patananan, A.N., McCaffery, J.M., Niazi, K., et al. (2016). Mitochondrial Transfer by Photothermal Nanoblade Restores Metabolite Profile in Mammalian Cells. Cell metabolism 23, 921-929.
  2. Wu, Y.C., Wu, T.H., Clemens, D.L., Lee, B.Y., Wen, X., Horwitz, M.A., Teitell, M.A., and Chiou, P.Y. (2015). Massively parallel delivery of large cargo into mammalian cells with light pulses. Nature methods 12, 439-444.
  3. Wu, T.H., Wu, Y.C., Sagullo, E., Teitell, M.A., and Chiou, P.Y. (2015). Direct Nuclear Delivery of DNA by Photothermal Nanoblade. Journal of laboratory automation 20, 659-662.
  4. Teh, B.E., French, C.T., Chen, Y., Chen, I.G., Wu, T.H., Sagullo, E., Chiou, P.Y., Teitell, M.A., Miller, J.F., and Gan, Y.H. (2014). Type three secretion system-mediated escape of Burkholderia pseudomallei into the host cytosol is critical for the activation of NFkappaB. BMC microbiology 14, 115.
  5. Yamane, D., Wu, Y.C., Wu, T.H., Toshiyoshi, H., Teitell, M.A., and Chiou, P.Y. (2014). Electrical impedance monitoring of photothermal porated mammalian cells. Journal of laboratory automation 19, 50-59.
  6. Riahi, R., Dean, Z., Wu, T.H., Teitell, M.A., Chiou, P.Y., Zhang, D.D., and Wong, P.K. (2013). Detection of mRNA in living cells by double-stranded locked nucleic acid probes. The Analyst 138, 4777-4785.
  7. Xu, J., Teslaa, T., Wu, T.H., Chiou, P.Y., Teitell, M.A., and Weiss, S. (2012). Nanoblade delivery and incorporation of quantum dot conjugates into tubulin networks in live cells. Nano letters 12, 5669-5672.
  8. French, C.T., Toesca, I.J., Wu, T.H., Teslaa, T., Beaty, S.M., Wong, W., Liu, M., Schroder, I., Chiou, P.Y., Teitell, M.A., et al. (2011). Dissection of the Burkholderia intracellular life cycle using a photothermal nanoblade. Proceedings of the National Academy of Sciences of the United States of America 108, 12095-12100.
  9. Wu, T.H., Teslaa, T., Kalim, S., French, C.T., Moghadam, S., Wall, R., Miller, J.F., Witte, O.N., Teitell, M.A., and Chiou, P.Y. (2011). Photothermal nanoblade for large cargo delivery into mammalian cells. Analytical chemistry 83, 1321-1327.
  10. Wu, T.H., Teslaa, T., Teitell, M.A., and Chiou, P.Y. (2010). Photothermal nanoblade for patterned cell membrane cutting. Optics express 18, 23153-23160.
  11. Lin, M.Y., Wu, Y.C., Lee, J.A., Tung, K.W., Zhou, J., Teitell, M.A., Yeh, J.A., and Chiou, P.Y. (2016). Intracellular Delivery by Shape Anisotropic Magnetic Particle-Induced Cell Membrane Cuts. Journal of laboratory automation 21, 548-556.

Cell Sorting Platforms

  1. Chen, Y., Chung, A.J., Wu, T.H., Teitell, M.A., Di Carlo, D., and Chiou, P.Y. (2014). Pulsed laser activated cell sorting with three dimensional sheathless inertial focusing. Small 10, 1746-1751.
  2. Chen, Y., Wu, T.H., Kung, Y.C., Teitell, M.A., and Chiou, P.Y. (2013). 3D pulsed laser-triggered high-speed microfluidic fluorescence-activated cell sorter. The Analyst 138, 7308-7315.
  3. Wu, T.H., Chen, Y., Park, S.Y., Hong, J., Teslaa, T., Zhong, J.F., Di Carlo, D., Teitell, M.A., and Chiou, P.Y. (2012). Pulsed laser triggered high speed microfluidic fluorescence activated cell sorter. Lab on a chip 12, 1378-1383.
  4. Park, S.Y., Wu, T.H., Chen, Y., Teitell, M.A., and Chiou, P.Y. (2011). High-speed droplet generation on demand driven by pulse laser-induced cavitation. Lab on a chip 11, 1010-1012.
  5. Kung, Y.C., Huang, K.W., Chong, W., and Chiou, P.Y. (2016). Tunnel Dielectrophoresis for Tunable, Single-Stream Cell Focusing in Physiological Buffers in High-Speed Microfluidic Flows. Small 12, 4343-4348.
  6. Kung, Y.C., Huang, K.W., Fan, Y.J., and Chiou, P.Y. (2015). Fabrication of 3D high aspect ratio PDMS microfluidic networks with a hybrid stamp. Lab on a chip 15, 1861-1868.

Cell Diagnostics Platforms

  1. Kim, D.N., Teitell, M.A., Reed, J., and Zangle, T.A. (2015). Hybrid random walk-linear discriminant analysis method for unwrapping quantitative phase microscopy images of biological samples. Journal of biomedical optics 20, 111211.
  2. Zangle, T.A., Teitell, M.A., and Reed, J. (2014). Live cell interferometry quantifies dynamics of biomass partitioning during cytokinesis. PloS one 9, e115726.
  3. Zangle, T.A., Chun, J., Zhang, J., Reed, J., and Teitell, M.A. (2013b). Quantification of biomass and cell motion in human pluripotent stem cell colonies. Biophysical journal 105, 593-601.
  4. Zangle, T.A., Burnes, D., Mathis, C., Witte, O.N., and Teitell, M.A. (2013). Quantifying biomass changes of single CD8+ T cells during antigen specific cytotoxicity. PloS one 8, e68916.
  5. Chun, J., Zangle, T.A., Kolarova, T., Finn, R.S., Teitell, M.A., and Reed, J. (2012). Rapidly quantifying drug sensitivity of dispersed and clumped breast cancer cells by mass profiling. The Analyst 137, 5495-5498.
  6. Reed, J., Chun, J., Zangle, T.A., Kalim, S., Hong, J.S., Pefley, S.E., Zheng, X., Gimzewski, J.K., and Teitell, M.A. (2011). Rapid, massively parallel single-cell drug response measurements via live cell interferometry. Biophysical journal 101, 1025-1031.